African Journal of
Health Sciences and Technology

FACULTY OF HEALTH SCIENCES AND TECHNOLOGY, COLLEGE OF MEDICINE, UNIVERSITY OF NIGERIA
  • Abbreviation: Afr. J. Health Sci. Technol.
  • Language: English
  • ISSN: 2805-4202
  • DOI: 10.5897/AJHST
  • Start Year: 2019
  • Published Articles: 38

Full Length Research Paper

Automated image analysis and Artificial Intelligence (AI) in breast cancer diagnosis: A systematized literature review

Debrah Ebenezer Lartey
  • Debrah Ebenezer Lartey
  • Department of Biomedical Engineering Technology, Koforidua Technical University, Koforidua, Ghana
  • Google Scholar
Debrah Ebenezer Lartey
  • Debrah Ebenezer Lartey
  • Department of Biomedical Sciences and Engineering, Mbarara University of Science and Technology, Mbarara, Uganda
  • Google Scholar
Ofori Eric Kwasi
  • Ofori Eric Kwasi
  • School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana
  • Google Scholar
Wasswa William
  • Wasswa William
  • Department of Biomedical Sciences and Engineering, Mbarara University of Science and Technology, Mbarara, Uganda
  • Google Scholar


  •  Received: 12 March 2025
  •  Accepted: 30 October 2025
  •  Published: 30 November 2025

Abstract

Breast cancer is a leading global health concern and the primary cause of female mortality worldwide. With incidence projected to exceed 3 million by 2040, timely and accurate diagnosis is critical to reduce mortality and improve clinical outcomes. There is a growing need to automate breast cancer diagnosis and classification. Artificial intelligence (AI) can enhance the efficiency, reliability, and precision of breast cancer detection, leading to better patient prognoses. This study provides a comprehensive review of recent advancements in automated breast cancer detection using mammograms. This survey examines AI applications in breast cancer diagnosis and classification via mammography over a 15-year period, from 2008 to 2023. A systematic review of 50 journal articles from PubMed, Google Scholar, Scopus, and Institute of Electrical and Electronics Engineers (IEEE) was conducted using keyword combinations including: artificial intelligence, mammograms, and breast cancer diagnosis. Findings revealed that most studies used a single dataset for validation, with limited use of multiple datasets. Thresholding and region-based segmentation were commonly employed. Classification approaches varied widely, including transfer learning, deep learning models, ensemble methods, and hybrid techniques, which often combined architectures to improve accuracy. This review highlights how dataset selection and segmentation techniques influence model performance. AI-based systems show significant potential in supporting radiologists by improving diagnostic accuracy, reducing interpretation time, and ultimately enhancing patient outcomes.
 
Key words: Artificial Intelligence (AI), mammogram, breast cancer diagnosis.